Services / Products
GenoSPYD : Rapid Microbiology (RNA quantification , sensitive, only viable organisms, 3 hours) for clean and sterile products and medical devices
Choosing a rapid microbiology testing system compatible with the product’s critical quality attributes, cGMP/GLP regulations, and validation requirements is crucial. GenoSPYD, the rapid RNA test (3 hours) for Total Viable Organisms and specific organisms applied to water testing, pharma testing, endoscope & hygien controls (surface, air), and for all filtered products. GenoSPYD solutions reduce product release cycle time, cost, and labor time via automation (high throughput, real-time data analysis). GenoSPYD also facilitates investigations by generating earlier results.
GenoSPYD products solution is available on any thermocycler instrument
GenoSPYD preloaded solution is available with the MIC thermocycler instrument
Customer can order at the same time several GenoSPYD kit to cover the analytical need. All microbiological panels are analyzed with the same PCR condition
TBC (Total Bacteria Count)
TYMC (Total Yeast & Mold Count)
TVO (Total Viable Organisms)
E.coli
Enterococcus spp
Staphylococcus aureus
Pseudomonas aeruginosa
GenoSPYD with the adapted pre-analytical solution can be use for sterility testing (1CFU), hygien – medical devices testing (25-40 CFU) (ultraclean) and environnemental (100-200 CFU) testing (clean).
Microsherlock : a new possibility of personalized Q-PCR panels for infectious and microbiological contaminants.
Rapid personalized DNA/RNA test (3 hours) infectious-microbial panels :
Gastro- Enteric panel (26 bacteria-parasite-virus) from stool specimen
Ocular infection panel (10 bacteria-parasite-virus) from eye swab specimen
Sepsis universal panel (all gram+, gram- and yeast & fungus) from blood
Urinary tract infection panel (10 bacteria) from filtered urine specimen
Food/Feed/Wine contamination panel (bacteria – yeast & mold – virus)
Microsherlock is a preloaded solution available with the MIC thermocycler instrument
Microsherlock panel kit is 4 selected infectious-microbial targets (384 MIC PCR reactions for 96 specimens)
Customer can order at the same time several panels to cover the analytical need
All panels are analyzed with the same MIC PCR condition
List of available panels and infectious-microbial targets is available on request
As more infectious and microbiological micro-organisms are discovered around the world in relation with disease, hygiene and contamination BlueDNAcompanion is taking the lead in developing a rapid method for personalized panels and accurate molecular biology solution. Microsherloks solution allows detection of multiple pathogens in a single test panel selected by clinicians and biologists. Microsherlock is a preloaded solution available with the MIC thermocycler instrument
Microsherlock panel kit is 4 selected infectious-microbial targets (384 MIC PCR reactions for 96 specimens)
Customer can order at the same time several panels to cover the analytical need
All panels are analyzed with the same MIC PCR condition
Microsherlock is a preloaded solution available with the MIC thermocycler instrument
Microsherlock panel kit is 4 selected infectious-microbial targets (384 MIC PCR reactions for 96 specimens)
Customer can order at the same time several panels to cover the analytical need
All panels are analyzed with the same MIC PCR condition
List of complete available panels and infectious-microbial targets and instruction for use (IFU) is available on request at info@microsherlock.com
Microsherlock panels are for Research Used Only (RUO)
MIC thermocycler and automated nucleic acid extraction instruments can be ordered from local distributors
AmoyDX : Detecting DNA mutation in FFEP cancer tissue and circulating fluids
BlueDNAcompanion is working with AmoyDX, the world wide leader company that focuses on detecting mutations and measuring gene expression in FFPE cancer tissues and circulating fluids. BlueDNAcompanion represent AmoyDX in France .The assays are based on a proprietary real-time PCR technology called “ADx-ARMS” with outstanding sensivity (1%) and accuracy (99%). The assays are easy to perform, provide results in 90 minutes, and have been validated on several PCR instruments that are commonly used in diagnostic laboratories (Roche LC 480, ABI, Qiagen RotorGene, Biorad CFX). NGS solution is now available for 10 genes (panel essential NGS. Amoy Diagnostics and AstraZeneca work closely together to faster the growth of molecular diagnostic testing for lung cancer patients in mainland China. AmoyDx supplies EGFR tests to AstraZeneca.
SANSURE : HPV Detection and Genotyping
The increasing need for HPV testing and genotyping has led to the integration of several technical solutions (rapid test, automated, point of Care).
Our solution make the full process analysis possible in 10 min labor time with the manual solution, 5 minutes labor time with the Point of care solution. The full autolated solution make possible the analysis of 96 samples in 3 hours.
15 Genotyping are available with manual and automated solution.
VOLATONOMICS : VOCs in body fluids (saliva, urine…)
There is an increasing interest in developing new biomarkers such as volatile organic compounds (VOCs) in body fluids to improve the following :
Accurate medical diagnosis
Therapeutic monitoring and prognosis
Drug efficiency
Physiological investigation.
Volatile compounds of human body are a result of the combination of hundreds of emitted odorous and non-odorous molecules.
VOCs are the useful biomarkers source for monitoring body state of health for enhanced personalized treatment (drug treatment efficiency, prognosis decision…). More than 1840 VOCs appearing in exhaled breath, skin emanations, urine, saliva, human breast milk, blood, tears, vitreous humor and feces.
A variation of normal VOCs pattern could be due to the alteration of specific biochemical pathways in the body. The rational for this approach is that metabolic changes of the disease cells can lead to a cellular oxidative stress, causing the appearance or increase in VOCs specific to the disease exuded into circulating fluids (blood, urine, saliva…). VOCs are mixed in body fluids and composition is depending on whether a cell is healthy or cancerous, sensitive or not to treatment as well as prognostic. BlueDNAcompanion offer a standardized protocol with limited clinical samples to develop and pre-valid a set of new VOCs biomarkers.
Please feel free to let us know your needs (body fluid, pathology…), we will design and conduct the VOCs study for you.
VOLATONOMICS : Off flavour
Any modification of the usual smell or taste from a product has consequences on the image of its quality. Odour modification can have a lot of causes. It can be due to, for example, chemical or bacterial contaminations, the quality of raw products, the conditions of storage or from the packaging. Identification of volatile compounds leads to the determination of the origin of taste and smell defects. Extraction and concentration of volatile compounds are run with solvent free techniques. Separation and identification are made by gas chromatography and mass spectrometry. The results are interpreted by taking into account all the parameters linked to the analyzed product either by a biochemical approach (contamination by raw products or processing) or by a chemical approach (external contamination). Explanation of results is made with an internal data bank given odor, taste, thresholds and toxicity of each identified volatile compound. BlueDNAcompanion specialization is the customized analysis according to the product and defect.